Description: Ketamine Drug Label Vintage Advertising Unisex T-Shirt Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression, a pain management tool, and as a recreational drug.[18] Ketamine is a novel compound that was derived from phencyclidine in 1962, in pursuit of a safer anesthetic with fewer hallucinogenic effects.[19][20] At anesthetic doses, ketamine induces a state of "dissociative anesthesia", a trance-like state providing pain relief, sedation, and amnesia.[21] The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation.[21] At lower, sub-anesthetic doses, ketamine is a promising agent for pain and treatment-resistant depression.[22] However, as with many antidepressants, the results of a single administration of ketamine wane with time.[23] The long-term effects of repeated use are largely unknown, and are an area of active investigation.[24][25][26] Liver and urinary toxicity have been reported among regular users of high doses of ketamine for recreational purposes.[27] Ketamine is an NMDA receptor pore blocker and that accounts for most of its actions, except the antidepressant effect, the mechanism of which is a matter of much research and debate. Ketamine was first synthesized in 1962 and approved for use in the United States in 1970.[18] It has been regularly used in veterinary medicine and was extensively used for surgical anaesthesia in the Vietnam War.[28] Along with other psychotropic drugs, it is on the World Health Organization's List of Essential Medicines.[29] It is available as a generic medication.[30] When used as a recreational drug, it is found both in powder and liquid form, and is often referred to as "Special K" for its hallucinogenic and dissociative effects.[31] Medical uses Anesthesia The use of ketamine in anesthesia reflects its characteristics. It is a drug of choice for short-term procedures when muscle relaxation is not required.[32] The effect of ketamine on the respiratory and circulatory systems is different from that of other anesthetics. It suppresses breathing much less than most other available anesthetics.[33] When used at anesthetic doses, ketamine usually stimulates rather than depresses the circulatory system.[34] Protective airway reflexes are preserved[35] and it is sometimes possible to administer ketamine anesthesia without protective measures to the airways.[32] Psychotomimetic effects limit the acceptance of ketamine; however, lamotrigine[36] and nimodipine[37] decrease psychotomimetic effects and can be counteracted also by benzodiazepines administered or propofol.[38] Ketofol is a combination of ketamine and propofol. Ketamine is frequently used in severely injured people and appears to be safe in this group.[39] It has been widely used for emergency surgery in field conditions in war zones,[40] for example, during the Vietnam War.[41] A 2011 clinical practice guideline supports the use of ketamine as a sedative in emergency medicine, including during physically painful procedures.[21] It is the drug of choice for people in traumatic shock who are at risk of hypotension.[42] Low blood pressure is dangerous for people with severe head injury[43] and ketamine is unlikely to lower blood pressure — conversely, often raising blood pressure, making it often the best suited for those with severe head injury.[44][45] Ketamine is an option in children, as the sole anesthetic for minor procedures or as an induction agent followed by neuromuscular blocker and tracheal intubation[40] In particular, children with cyanotic heart disease and neuromuscular disorders are good candidates for ketamine anesthesia.[38] Due to the bronchodilating properties of ketamine, it can be used for anesthesia in people with asthma, chronic obstructive airway disease, and with severe reactive airway disease including active bronchospasm.[40][38][46] Recreational use At sub-anesthetic doses ketamine produces a dissociative state, characterised by a sense of detachment from one's physical body and the external world that is known as depersonalization and derealization.[150] At sufficiently high doses, users may experience what is called the "K-hole", a state of dissociation with visual and auditory hallucination.[151] John C. Lilly, Marcia Moore, D. M. Turner, and David Woodard (amongst others) have written extensively about their own entheogenic and psychonautic experiences with ketamine.[152] Turner died prematurely due to drowning during presumed unsupervised ketamine use.[153] In 2006 the Russian edition of Adam Parfrey's Apocalypse Culture II was banned and destroyed by authorities owing to its inclusion of an essay by Woodard about the entheogenic use of, and psychonautic experiences with, ketamine.[154]:288–295 Recreational ketamine use has been implicated in deaths globally, with more than 90 deaths in England and Wales in the years of 2005–2013.[155] They include accidental poisonings, drownings, traffic accidents, and suicides.[155] The majority of deaths were among young people.[156] Because of its ability to cause confusion and amnesia, ketamine has been used for date rape.[157][138] Cheeky Money T-Shirts We do offer t-shirts manufactured by other companies from time to time please use this advertisement for size and color information for these products. All Gildan Activewear T-Shirts give a rich and structured look to the classic t-shirt and work great for layered streetwear outfits. Thanks to its durable fabric, Gildan t-shirts maintain sharp lines along the edges and last very long. Gildan T-Shirts •All Products are Hand Printed on the latest Direct to Garment equipment. •Cheeky Monkey Tees run true to size •100% Ring Spun Cotton (most colors) •Sport Grey is 90% cotton, 10% polyester •Ash Grey is 99% cotton, 1% polyester •Heather colors are 50% cotton, 50% polyester •Pre-shrunk jersey knit •Open-end yarn •Tubular construction •Taped neck and shoulders •Double seam at sleeves and bottom hem •Tear-away tag •Disclaimer: Dark color speckles throughout the fabric are expected for the color Natural. •Blank products are sourced from The United States, Mexico, Canada, The United Kingdom, Germany, Honduras, Nicaragua, Haiti, Dominican Republic, and Bangladesh. •Disclaimer: Dark color speckles throughout the fabric are expected for the color Natural. Return Policy •This product is made to order; therefore, it is not eligible for exchange or return. In the event of shipping damage or a manufacturer defect, please contact Customer Service. •We provide size charts in each advertisement, please refer to these size charts and compare an existing shirt that fits well with the included size chart to select the correct size. We do not exchange or accept returns for incorrect fit. 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Making products on demand instead of in bulk helps reduce overproduction, so thank you for making thoughtful purchasing decisions! Size guide LENGTH (inches)WIDTH (inches)S2818M2920L3022XL31242XL32263XL3328 LENGTH (cm)WIDTH (cm)S71.145.7M73.750.8L76.255.9XL78.7612XL81.3663XL83.871.1
Price: 26.99 USD
Location: Charlotte, North Carolina
End Time: 2024-02-29T01:16:48.000Z
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Brand: Cheeky Monkey Tees
Department: Unisex Adults
Size Type: Regular
Style: T-shirt
Type: T-shirt
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Color: White
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